Real Madrid will be out to retain top spot in La Liga when Malaga visit the Santiago Bernabeu on Saturday afternoon
Rafa Benitez’s side leapfrogged Barcelona to the summit in midweek thanks to a 2-1 victory at Athletic Bilbao and are 1/6 on to see off the struggling Costa del Sol club on home soil this weekend.
Gareth Bale and James Rodriguez may still be sidelined through injury but Isco has stepped up in their absence and will be eager to shine against his former club. The playmaker is 5/4 to get on the scoresheet.
Cristiano Ronaldo is also closing in on Raúl’s all-time goalscoring record and is 13/5 to open the scoring. The former Manchester United man may have five goals to his name so far this season but he has scored them all in one game.
Karim Benzema is the man in form in front of goal with goals in each of his last five Madrid outings and the Frenchman is 4/7 to make it six in a row this weekend.
Malaga are yet to win this season and are unlikely to get anything from their trip to the capital. Javi Gracia’s side have also failed to score in their last five Liga outings, making odds of 8/11 for another Madrid clean sheet look tempting.
A comfortable home win should be on the cards and a 3-0 scoreline offers odds of 24/5.
Barcelona looking for a response against Las Palmas
Barcelona will be like a wounded animal when they host Las Palmas at Camp Nou on Saturday.
Luis Enrique’s side lost top spot in midweek when they slumped to a surprise 4-1 defeat at his former club Celta Vigo and the Barca boss will be looking for a response against the Canary Islands club.
Odds of 1/10 reflect Barcelona’s tag of favourites for the match and despite a first win since returning to the top flight for Miguel Ángel Ramírez’s side, anything but defeat looks unlikely.
Jordi Alba should be in-line for a return to action after missing the midweek defeat but Rafinha and Thomas Vermaelen are still absent through injury.
The Catalan club have won eight of their last nine home matches in La Liga and have scored at least two goals in each of those victories.
Luis Suarez, Neymar and Lionel Messi will all be chomping at the bit to get on the scoresheet but for longer odds Ivan Rakitic is 9/1 to open the scoring.
The rest of La Liga
Valencia and Granada kick things off on Friday night at Mestalla and the hosts are desperate for three points after slumping to defeat at Espanyol in midweek.
Nuno Espirito Santo’s side have endured a hit-and-miss start to the campaign but are favourites to bag all three points against a visiting side who have lost four of their five league matches so far this term.
Los Che have drawn their last three league matches and are 10/3 to make it four in a row. However, they have seen off Granada in seven of their last eight meetings.
Goals have been hard to come by for the Mestalla club so don’t expect a comfortable home victory. A one-goal winning margin for Nuno’s side looks a good bet at 12/5.
Sevilla’s poor start to the season continued with defeat at Las Palmas in midweek and Unai Emery’s side are desperate for a home win against Rayo Vallecano on Saturday to lift them off the bottom of the table.
The Andalusians are 1/2 for a home win that would be their first of the season.
Nico Pareja, Ever Banega, Gael Kakuta, Adil Rami and Daniel Carrico are still absent through injury for Sevilla and former Juventus man Fernando Llorente will need to step up to get his side’s goals. The Spaniard is 4/1 to open the scoring.
Villarreal host Atletico Madrid on Saturday night in what looks set to be the match of the weekend on paper. Both have made impression starts to the season but something will have to give at El Madrigal.
Marcelino´s men are joint top of the table and Diego Simeone’s side sit just a point behind. Given the form of both sides a draw looks a good bet at 21/10.
Luciano Vietto could be in-line to feature against his former club and the Argentine is 13/5 to get on the scoresheet with his first goal in an Atleti shirt.
Celta Vigo have been one of the surprise packages of the season so far and they will look to continue their good form at Eibar on Saturday night.
The Galicians will go into the match on the crest of a wave thanks to a stunning 4-1 victory against Barcelona in midweek, a result that took them joint top of the table.
Eibar have started well but Celta’s form should see them leave Ipurua with all three points. Eduardo Berizzo’s side are 11/10 for the victory.
Spain international Nolito is man of the moment in attack and is 5/1 to open the scoring but former Liverpool man Iago Aspas also enjoyed himself in the victory over Barca and is 21/10 to score anytime.
It’s the battle of the newly-promoted clubs at El Molinon on Sunday afternoon as Sporting Gijon take on Real Betis.
Both clubs have made encouraging starts to life back in the top flight but both will look to bounce back from 2-1 defeats in midweek.
The clash should be a close one and odds of 9/4 for the sides to share the spoils looks the best bet.
Deportivo La Coruna and Espanyol should both be satisfied with the starts they’ve made this season and the pair face off at Riazor on Sunday afternoon.
Both won in midweek and are separated by just a point going into the game, meaning odds of 95/40 for the draw look good.
Unlike the clash in Gijon, both Depor and Espanyol have been in the goals lately so a goalscoring stalemate looks likely. Odds of 9/2 are offered for a 1-1 draw and for the hosts to be leading at half-time with the match finishing all square you can get longer odds of 12/1.
Getafe host Levante in the Spanish capital on Sunday and Fran Escriba’s side will look to take advantage of the visitors’ nine-match winless run in the league.
The hosts are 19/20 to collect three points but they are yet to score two goals in a match this term, making a comfortable win unlikely. A 1¬-0 win for Getafe offers odds of 4/1.
Stefan Scepovic has scored once since his summer arrival and is 5/1 to break the deadlock this weekend.
The first Basque derby match of the season between Real Sociedad and Athletic Bilbao takes place at Anoeta on Sunday night.
Athletic have already fallen to one derby defeat already this term, going down to Eibar, and will be eager to bounce back against their bitter rivals.
However, David Moyes’ men will be boosted by their much-needed first win of the season in midweek, a victory that took them above Athletic.
The sides look evenly matches going into the game and odds of 9/4 are offered for the derby to end in a share of the spoils.
Imanol Agirretxe was La Real’s hero in midweek with a hat-trick at Granada and he is 11/2 to score first in San Sebastian.
Aritz Aduriz is Athletic’s main threat in attack and odds of 5/1 are offered for the experienced frontman to open the scoring.
Odds are provided at time of writing, please check your betslip to confirm they have not changed before betting.